RNA Nanoparticle Formulation, Process and Characterization
R.K. DeLong, M.S., PhD and Eli Kraus PhD
Abstract: It is well documented that ribonucleic acid (RNA) plays an important role in molecular level regulation and control within cells and tissues. The role of RNA, especially messenger RNA (mRNA), in personalized medicine and drug development has been rapidly evolving. However, the journey of using RNA as a treatment option began as early as 1978 with the first delivery of mRNA to mouse cells using liposomes.