Whether you’re an academic researcher vetting therapeutic targets, a physician scientist preparing for IND filing, a startup team lead taking your first pipeline product to clinic, or a technical operations executive seeking novel technology solutions for next generation product development, the right partner can help remove obstacles, maximize efficiency, and meet milestones at an accelerated pace.
Landmark Bio does more than make cell and gene therapy, genome editing and mRNA products. In addition to our state-of-the-art facility for GMP manufacturing and quality control, we offer broad capabilities from translational research to process and analytical development, and regulatory CMC support, along with the expertise to develop and optimize drug development strategies with a line-of-sight from discovery to commercialization.
These wraparound services help academics, research hospitals, and life science companies forge a path from bench to clinic, and beyond.
It’s our cross-sector network of top-tier founding partners and collaborators, our new state-of-the-art facility, our extensive experience in developing and integrating novel technologies, and our unique ability to advise and consult on essential drug development issues that make us such a desirable development partner.
Landmark Bio is growing. Join our team and help us turn today’s cutting-edge research into tomorrow’s breakthrough therapies.
We look forward to hearing from you. Get in touch to bring your development project to life or become a valued technology collaborator.
300 North Beacon Street
Watertown, MA 02472
Beate Mueller-Tiemann
CHIEF TECHNOLOGY OFFICER, CYTIVA
Dr. Beate Mueller-Tiemann’s career has reflected the entire pharma value chain from early target discovery, lead generation, lead optimization, cell line development, chemical manufacturing and control (CMC) production and commercial manufacturing for both Biologics and Synthetic Molecule therapeutics. Beate joined Cytiva as Chief Technology Officer in early 2023, having previously held senior leadership positions at Sanofi and Bayer.
Beate is an elected member of the Board of the Dechema, German Society for Chemical Engineering and Biotechnology. She supports female talents with mentoring programs and is a member of FiDAR, an association that works towards increasing the representation of women on German corporate boards.
She is based in Frankfurt, Germany.
Shanti Chari
VICE PRESIDENT, DIGITAL TECHNOLOGIES & INNOVATION
Kris Ward
VICE PRESIDENT, CORPORATE DEVELOPMENT & LICENSING
Todd Howren
Todd Howren brings over 25 years of experience in the life sciences industry, including ten years of business development leadership experience. Before joining Landmark Bio, Todd served as the Vice President of Sales at Aldevron and later as the head of Aldevron’s RNA Business Unit. As the Vice President of Global Commercial Operations at Meridian Bioscience, Todd led the Life Sciences Division’s Sales, Marketing, and Product Management. He also spent nearly 15 years at Thermo Fisher Scientific Corporation in various business development positions of increasing responsibility, ending as the lead for global strategy focusing on human molecular diagnostics and mRNA therapeutics. After graduate school, Todd began his career at Sigma-Aldrich, ending as National Sales Manager for Functional Genomics.
Todd earned his Bachelor of Science in Biology from Baylor University, Waco, Texas, and his Ph.D. in Physiology and Biophysics from the University of Arkansas for Medical Sciences, Little Rock, Arkansas. He has published several scientific papers and is an accomplished presenting expert at conferences and symposiums worldwide.
Emmanuel Abate
PRESIDENT GENOMIC MEDICINE AND HEAD OF SUSTAINABILITY AND CORPORATE SOCIAL RESPONSIBILITY, CYTIVA
Emmanuel Abate works to bring out the best in his team so they can better serve the scientific community working on the next medical breakthrough. The Genomic Medicine business includes solutions to help advance the discovery and manufacturing of viral vector, cell therapies, and nucleic acid- based therapies.
As he is deeply connected to nature, our surroundings, and our role in protecting people and the planet, Emmanuel also leads the company-wide Sustainability and Corporate Social Responsibility strategy. This role involves continuous improvement in the way the company looks after customers and associates and enables positive societal change.
Emmanuel’s career began in 1999 with GE Healthcare, where he worked in business development and eBusiness. He earned his MBA in 2004 and joined the Boston Consulting Group from 2004 – 2007, based in Paris. When he returned to GE Healthcare in 2007, he served in product and commercial leadership positions for Interventional Imaging, Women’s Health Imaging, and Radiology.
In 2018, Emmanuel became the General Manager of Genomics and Cellular Research, when the business was part of GE Healthcare Life Sciences, now Cytiva.
Emmanuel was appointed to his current position in September 2022. He lives in Paris with his wife and son.
VICE PROVOST FOR RESEARCH, HARVARD
In his role as Vice Provost for Research, John H. Shaw works to support the research enterprise of the University, including its twelve schools, fifteen practicing hospitals, and roughly 30 initiatives, centers, and institutes that bring together faculty across campus and University partners. He helps to advance Harvard’s mission by enabling foundational and transformative research and developing core research support. In this role, John serves on Boards and various committees of the Wyss Institute for Biologically Inspired Engineering, the Ragon Institute, the Kempner Institute for Natural and Artificial Intelligence, the Massachusetts Green High Performance Computing Center (MGHPCC), and other programs that support life and physical science research and technology translation. His office also helps the University navigate the federal regulatory landscape for research funding received by Harvard (totaling nearly $1 billion annually) and associated compliance requirements.
John also serves as the Harry C. Dudley Professor of Structural and Economic Geology in the Earth and Planetary Sciences (EPS) Department, and Professor of Environmental Science and Engineering in the Paulson School of Engineering and Applied Science (SEAS). He is a structural geologist and applied geophysicist who investigates the nature of faulting in the earth’s crust, with applications to earthquake science. His research is also focused on energy systems and carbon storage, and the environmental impacts of these activities. Shaw offers courses on these topics through FAS and SEAS.
John served as chair of the EPS Department for thirteen years, supporting faculty, affiliated scientists, students, and staff. Activities in this role included strategic planning, faculty hiring and evaluation; oversight of student academic programs; fiscal management and planning; research compliance; fundraising; alumni relations; diversity and inclusion initiatives; and oversight of lab renovations and building operations. John has served on several School- and University-level committees focused on professional conduct and research policy. He recently served as the Chair of the Board of the Southern California Earthquake Center, an international research organization involving more than 90 institutions with federal and private sector funding sources. He is also co-founder of Seismix Reservoir Management, LLC, a firm that helps to assess environmental hazards of energy-related operations for companies, regulatory groups, and others.
Will Channell
SENIOR VICE PRESIDENT, FINANCE
Will Channell has over 20 years of experience in corporate finance and strategy and over 15 years of experience working in the life sciences industry. As Senior Vice President of Finance, Will is responsible for all aspects of Landmark Bio’s financial operations and planning. Prior to joining Landmark Bio, Will was Chief Financial Officer of RADD Pharmaceuticals, a seed-stage, preclinical oncology company, where he was responsible for Finance, Legal, HR, and IT services.
Will has built global finance teams and infrastructure to support multiple product launches and assisted in capital raising for a number of life sciences companies including argenx, Orchard Therapeutics and Alexion Pharmaceuticals. Will also held corporate finance and strategy roles of increasing responsibility at Covidien (now Medtronic) and Cardinal Health.
Will holds a BS in Biology from Pennsylvania State University and an MBA in Finance from Boston College.
Olga Mollin
VICE PRESIDENT, TECHNICAL OPERATIONS & SITE HEAD
Olga Mollin brings more than 20 years biopharmaceutical industry experience to her new role at Landmark Bio. Most recently, she was Vice President at Affinivax, where she led the company’s Global Manufacturing and Supply organization and facilitated the subsequent integration into GSK Vaccines organization. Prior to that, Olga was a member of the Sanofi External Supply leadership team, primarily in the rare disease, oncology, and rare blood disease franchise areas. She also spent over 15 years in positions of increasing responsibility at Lonza, including key leadership roles in Manufacturing, Contract Management and QA.
Olga earned a Master’s in Business Administration from University of New Hampshire and a B.S. in Biotechnology from Dublin City University, Ireland.
Andy Topping
CHIEF SCIENCE OFFICER, FUJIFILM DIOSYNTH BIOTECHNOLOGIES
Andy has worked in contract development and manufacture of biologics for almost 30 years. Originally trained as a molecular biologist with a Ph.D. from the University of Wales in Cardiff, he has led development and manufacturing projects bringing over 100 products from microbial and mammalian expression systems into the clinic. As Chief Scientific Officer for the global CDMO Fujifilm Diosynth Biotechnologies, he is responsible for science and innovation across the company’s sites in Europe and the US in areas spanning from large scale commercial manufacture of monoclonal antibodies to supporting first in man gene therapies. Andy is a strong believer in simplicity and standardization as the way to move swiftly in development while providing a strong underpinning for future success.
Tim Charlebois
SENIOR FELLOW AT NIIMBL, FORMER VICE PRESIDENT OF TECHNOLOGY AND INNOVATION STRATEGY AT PFIZER
Dr. Tim Charlebois retired from Pfizer after a 30-year career with the company including legacy companies Wyeth and Genetics Institute. His technical expertise and experience included molecular biology, cell line development, characterization, cGMP cell banking and testing, cell culture and drug substance process development. He was deeply involved in the development and registration of a number of early biopharmaceutical products including Recombinate (rhFVIII), BeneFIX (rhFIX), Neumega (rhIL-11), Infuse (rhBMP2), ReFacto AF (BDDFVIII), and Enbrel (etanercept).
Mark Namchuk
EXECUTIVE DIRECTOR OF THERAPEUTIC TRANSLATION AT HARVARD MEDICAL SCHOOL
Mark Namchuk PhD is a professor of the practice of biological chemistry and molecular pharmacology and the executive director of therapeutics translation at Harvard Medical School. In this later role, Namchuk works with HMS scientists to identify and harness basic insights and move them towards clinical therapies, while training the next generation of therapeutics investigators. He has overall responsibility for the HMS therapeutics initiative which includes an on-campus Biotech incubator (the Blavatnik LifeLab Longwood), a scientific core dedicated to supporting therapeutics discovery in faculty labs at HMS and affiliated institutions and educational programs in therapeutics at the graduate and post-doctoral level. His current research interests focus on drug discovery, in particular antivirals for the treatment of COVID-19.
Namchuk joined HMS in 2020 after a 24-year research and development career in the biotech industry, in the arenas of drug discovery, translational science and pharmaceutical development. In 2015, he joined Alkermes as senior vice president of research and nonclinical and pharmaceutical development. Previously, Namchuk held a number of senior research positions over a 17 year career at Vertex including senior vice president of Research.
Over more than two decades he has directed drug discovery efforts in numerous therapeutic areas, including infectious disease, oncology, neurodegenerative and psychiatric disorders, immune-mediated inflammatory disease, inflammatory bowel disease and orphan diseases, including cystic fibrosis. These responsibilities encompassed scientific oversight of the various disciplines in discovery science, DMPK, preclinical and clinical biomarker development, nonclinical safety and pharmaceutical development. Namchuk obtained a BSc in Chemistry for the University of Alberta, a PhD in Bio-organic chemistry from University of British Columbia and was an HFSP post doctoral fellow at UCSF.
JC Gutiérrez-Ramos
CHIEF SCIENCE OFFICER, DANAHER CORPORATION
Jose-Carlos has served as Chief Science Officer for Danaher Corporation since January 2021. Before joining Danaher, he served for 18 years as an R&D executive for Abbvie, Pfizer, Takeda and GSK, where he was responsible for Global Discovery, Biotherapeutics R&D, and Immunology & Inflammation R&D, respectively. Teams under his direction have delivered three drugs to market and six others are currently in phase 3 clinical development. During the five years prior to joining Danaher, he was the Founding CEO and President for two Biotechnology companies: Repertoire Immune Medicine and Synlogic Inc. During his tenure as Biotech CEO, he took two pioneering technology platforms (Synthetic biology and Immune TCR pMHC decoding) to the clinic and then to the public markets. He serves as director on the board of several biotechnology companies. He started his career as an academic researcher with faculty positions at the Basel Institute in Switzerland and Harvard Medical School in Boston.
Amy Wagers
PROFESSOR AND CO-CHAIR OF DEPARTMENT STEM CELL AND REGENERATIVE BIOLOGY, HARVARD UNIVERSITY
Dr. Amy Wagers’ substantial contributions to science, published in more than 150 primary research and review articles, have brought to light novel regulators (both intrinsic and extrinsic) of stem cell activity in injury repair, degenerative disease, and malignancy, and highlighted key roles for specific blood-borne mediators, cellular niches, inflammatory and metabolic cues in coordinating the functions of stem cells and their progeny throughout the body.
She has also established groundbreaking methods for manipulating stem cell genomes in situ — work that opens new avenues of research and new possibilities for treating congenital and age-related diseases.
In addition to her work at the Harvard Stem Cell Institute, Wagers is a senior investigator in the section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.
Stacy Springs
EXECUTIVE DIRECTOR, MIT CENTER FOR BIOMEDICAL INNOVATION
Dr. Stacy Springs is the Executive Director at the MIT Center for Biomedical Innovation (CBI). The Center integrates the Institute’s technical, scientific, and management expertise to solve complex biopharmaceutical challenges. CBI leads multi-stakeholder, multidisciplinary research and educational initiatives with real world impact, including MIT’s Biomanufacturing Consortium, (BioMAN), and it’s Consortium on Adventitious Agent Contamination in Biomanufacturing, (CAACB). Dr. Springs is a principle investigator on several research programs in biologics manufacturing, from application of data analytics and PAT in the continuous production of monoclonal antibodies, viral vectors and vaccines; to development of innovative rapid sterily tests and new approaches to adventitious agent contamination through long read sequencing. Dr. Springs is part of the leadership of SMART CAMP, an interdisciplinary research group focused on Critical Analytics for Manufacturing Personalized-Medicine at the Singapore-MIT Alliance for Research and Technology (SMART) and serves as the Chair of Landmark Bio’s Science and Technology Committee.
Dr. Springs’ research interests include biopharmaceutical development and manufacturing, risk management, regulatory and translational science and food safety and food supply chains. She holds a PhD in Chemistry from the University of Texas at Austin and gained postdoctoral training in protein and biophysical chemistry at Princeton University.
Laurence Cooper
FORMER PROFESSOR MD ANDERSON, FORMER CHIEF EXECUTIVE OFFICER ZIOPHARM ONCOLOGY
Dr Laurence Cooper has contributed to the development of many therapies and cutting-edge technologies including in immuno-oncology where he developed and implemented novel immunotherapies raising large amounts of capital through grants, philanthropy and investors. He established relationships with academia through a Collaborative Research and Development Agreement (CRADA) with Dr. Steven Rosenberg at National Cancer Institute and a comprehensive Research Agreements with MD Anderson Cancer Center.
While a public CEO and Director at Ziopharm Oncology, Laurence helped develop viral-based therapies using genetic switches to control interleukins as monotherapy and in combinations as well as T-cell therapies based on non-viral gene transfer and cytokine-driven cell biology.
Martin Meeson
BOARD MEMBER, CHIEF EXECUTIVE OFFICER, FUJIFILM DIOSYNTH BIOTECHNOLOGIES
Martin Meeson is a seasoned executive who brings extensive global experience to the Biotech and Pharmaceutical markets. Martin was named Chief Executive Officer on April 1st, 2020 after serving as Chief Operating Officer and President at of our US FDB operations (North Carolina and Texas). Previously Martin served as Chief Financial Officer for the US. Prior to this, Martin worked for the Fujifilm Diosynth organization for over 6 years, holding leadership positions at the United Kingdom site, including Head of Finance and IT. Before joining Fujifilm Diosynth he was Finance Director at Oxford Chemicals where he was responsible for all aspects of Finance, IT, and Purchasing. He has also held leadership positions at Hibernia Foods, ICI/Dupont and KPMG.
Amanda Halford
BOARD MEMBER, PRESIDENT, BIOPROCESS, CYTIVA
Amanda Halford has her eyes on growth. A chemist, she combines the scientific view with business acumen and experience. She commands a strategic view of how to expand Cytiva business through customer intimacy, mergers and acquisitions, licensing, and technology transfer.
Amanda joined Cytiva in January 2019 as General Manager, Strategy and Business Development. She quickly transitioned to Senior Vice President, Sales, Service and Commercial Operations. Passionate about enabling customers to deliver the right therapy to the right patient at the right time, she is focused on guiding the bioprocess, cell and gene therapy, and genomics and cellular research businesses to be even stronger partners to researchers, clinicians and medical professionals.
Before coming to Cytiva, she held the roles of Executive Vice President, Life Sciences Division and Chief Commercial Officer at EAG Laboratories, a San Diego, California-based scientific services company. There she oversaw a business strategy to diversify the customer base, extend market share and accelerate growth.
For 15 years she served in various executive capacities at Sigma Aldrich across both the research and SAFC businesses, leading a number of global businesses including the Chemistry franchise, the industry leading Business platform and the Academic Research business portfolio.
Amanda is a fierce believer in developing girls to be leaders of the future. To that end, she served as a Board Member of the Girl Scouts of Eastern Missouri from 2016-2019, where she was a Member of the STEM committee and advisory member of the strategic planning committee.
She graduated top of her class with an Executive MBA from EM Lyon and holds a BSc Honours in Chemistry from Imperial College, London. Amanda is fluent in French and English and brings a truly global perspective having lived, worked and travelled extensively around the world.
Cynthia Barnhart
BOARD MEMBER, PROVOST MIT
Cynthia Barnhart is Provost, Professor of Operations Research, and Ford Foundation Professor of Engineering at MIT. Barnhart has served as MIT’s Chancellor, as the Associate and Acting Dean for the School of Engineering, and as co-director of the Operations Research Center and the Center for Transportation and Logistics.
Barnhart’s teaching and research are in the areas of large-scale optimization and analytics, with a focus on applications in transportation and logistics systems. She has supervised scores of graduate and undergraduate theses across a range of disciplines, and has published widely in the flagship journals of her field.
Barnhart is an elected member of the National Academy of Engineering and the American Academy of Arts and Sciences, and is a fellow of the Institute for Operations Research and Management Science (INFORMS). She has served as the President of INFORMS, the President of the INFORMS Women in Operations Research and Management Science, and the President of the INFORMS Transportation Science and Logistics Society. Barnhart’s awards include the INFORMS President’s Award, the INFORMS Franz Edelman Prize for Achievement in Operations Research and the Management Sciences, the National Science Foundation Presidential Young Investigator Award, and honorary doctorates from the École Polytechnique Fédérale de Lausanne and the University of Toronto.
Barnhart received her SM in transportation in 1986 and her PhD in 1988 from MIT.
Alan Garber
BOARD CHAIR, PROVOST, HARVARD UNIVERSITY
Provost Alan M. Garber serves as Harvard University’s chief academic officer. He is also the Mallinckrodt Professor of Health Care Policy at Harvard Medical School, a Professor of Economics in the Harvard Faculty of Arts and Sciences, Professor of Public Policy in the Harvard Kennedy School of Government, and Professor in the Department of Health Policy and Management in the Harvard T.H. Chan School of Public Health. An economist and physician, he studies methods for improving health care productivity and health care financing.
As Provost, Dr. Garber oversees academic activities throughout the university, with direct responsibility for inter-school initiatives, faculty development, research policy, international affairs, and advances in learning. The Harvard Art Museums, the Harvard Library, Harvard University Health Services, HarvardX, the American Repertory Theater, and the Arnold Arboretum are among the organizations reporting to the Provost.
Before becoming Provost at Harvard in 2011, Dr. Garber was the Henry J. Kaiser Jr. Professor and a Professor of Medicine, as well as a Professor of Economics, Health Research and Policy, and Economics in the Graduate School of Business (by courtesy) at Stanford University. At Stanford, he founded and directed the Center for Health Policy and the Center for Primary Care and Outcomes Research, and served as a Staff Physician at the Department of Veterans Affairs Palo Alto Health Care System.
Dr. Garber is an Elected Member of the Association of American Physicians, the National Academy of Medicine, and the American Academy of Arts and Sciences. He is also an Elected Fellow of the American Association for the Advancement of Science, the American College of Physicians and the Royal College of Physicians. A summa cum laude graduate of Harvard College, Dr. Garber received a PhD in Economics from Harvard and an MD with research honors from Stanford.
Aileen Baquiran
VICE PRESIDENT BUSINESS OPERATIONS
Aileen has over 20 years of experience in the life sciences industry. As Vice President of Business Operations, Aileen is responsible for Program Management, People Operations, IT Services and Corporate Communications. Prior to Landmark Bio, Aileen was VP Global Supply Chain & Business Operations at Orchard Therapeutics where she designed and implemented the commercial distribution and site qualification process for one of the first commercially approved gene therapies.
Aileen also held project management and supply chain management roles of increasing responsibility at Dermira, Jazz Pharmaceuticals and Johnson & Johnson. She earned her Bachelor of Science in Industrial Engineering from Cal Poly, San Luis Obispo, and MBA from the University of San Francisco.
Michael Covington
CHIEF QUALITY & REGULATORY OFFICER
Michael Covington brings three decades of biotechnology, cellular, and gene therapy experience in areas including regulatory affairs, regulatory compliance, quality, validation, and manufacturing. He has demonstrated success in supporting innovative therapies including adeno-associated vector (AAV) gene therapies, autologous genetically modified hematopoietic stem and progenitor cell therapies for rare diseases, autologous genetically modified T cell immunotherapies, and other autologous immunotherapies, as well as recombinant protein therapeutics.
Most recently, Mr. Covington was the vice president of Regulatory Chemistry, Manufacturing, and Controls (CMC) for Novartis Gene Therapies. Prior to Novartis, he was vice president of Regulatory CMC for Orchard Therapeutics, and held leadership positions with Juno Therapeutics, Dendreon, and Amgen. He earned a B.A. in biology, cellular, and molecular biology from the University of Missouri-Columbia.
Gregg Nyberg
CHIEF TECHNOLOGY OFFICER
Gregg Nyberg, Ph.D., brings more than 20 years’ biopharmaceutical industry experience to his new role at Landmark Bio. Most recently, he was associate vice president at Merck, where he led the company’s biologics process development and clinical manufacturing organizations. He also spent nearly 15 years in positions of increasing responsibility at Amgen including key leadership roles in process development and cell sciences and technology.
Dr. Nyberg earned a Ph.D. in chemical engineering from the Massachusetts Institute of Technology and a B.S. in chemical engineering and petroleum refining from the Colorado School of Mines.
Ran Zheng
CHIEF EXECUTIVE OFFICER
Ms. Zheng is a biotechnology industry veteran who brings more than 25 years of experience in biotechnology operations across multiple geographies to Landmark Bio. Ms. Zheng most recently served as Chief Technical Officer at Orchard Therapeutics, a commercial-stage global gene therapy company specializing in HSC based gene therapies. In this role, Ms. Zheng established the technical operations function and manufacturing network, and advanced the company’s product pipeline, including the approval of Libmeldy™ – the first gene therapy product for metachromatic leukodystrophy. Ms. Zheng has also held leadership positions at several major biotechnology companies including Genzyme (now Sanofi) and Amgen. At Amgen, Ms. Zheng played a key role in building differentiating capabilities in manufacturing for clinical supply and commercial product launch to enable speed to clinic and speed to market strategies for Amgen’s innovative products.